The connection between "brotherhood" and "sisterhood" is combed to reflect the androgynous and spiritual connection between all which exists, which has ever existed, and which will ever exist. The concept that "I am also a You" is also reflected in the "11" vibration.
Master number 22:
Is the realization of the God source within the self, the recognition that God source is in the totality of existence, and understanding of the God source outside of self; a combined vibration of Self, Others & the Whole. The concept of the parallel dimension with respect to the four cardinal directions is reflected in the "22" vibration.